Peripheral Arterial Disease
Also called: PAD
Peripheral arterial disease (PAD) happens when there is a narrowing of the blood vessels outside of your heart. A substance made up of fat and cholesterol, called plaque, builds up on the walls of the arteries that supply blood to the arms and legs. The plaque causes the arteries to narrow or become blocked. This can reduce or stop blood flow, usually to the legs, causing them to hurt or feel numb. If severe enough, blocked blood flow can cause tissue death. If this condition is left untreated, a foot or leg may need to be amputated.
A person with PAD also has an increased risk of heart attack, stroke and transient ischemic attack. You can often stop or reverse the buildup of plaque in the arteries with dietary changes, exercise, and efforts to lower high cholesterol levels and high blood pressure.
National Heart, Lung, and Blood Institute
Start Here
- Peripheral Arterial Disease
(National Heart, Lung, and Blood Institute) - Peripheral Vascular Disease(American Heart Association)
Also available in Spanish
| Basics | Learn More | Multimedia & Cool Tools |
|---|---|---|
| Research | Reference Shelf | For You |
- Overviews
- JAMA Patient Page: Peripheral Arterial Disease(American Medical Association)
Also available in Spanish
- Peripheral Artery Disease (PAD)(Mayo Foundation for Medical Education and Research)
- Peripheral Artery Disease (PAD)(Society for Vascular Surgery)
- JAMA Patient Page: Peripheral Arterial Disease(American Medical Association)
- Latest News
- Aspirin Lowers Stroke Risk in Peripheral Artery Disease(05/12/2009, HealthDay)
- With Peripheral Artery Disease, Med Adherence Is Low(04/24/2009, HealthDay)
- Study Questions Screening for Leg Vessel Blockages(03/16/2009, HealthDay)
- Diagnosis/Symptoms
- Angiogram(Society for Vascular Surgery)
- Ankle-Brachial Index(Mayo Foundation for Medical Education and Research)
- Computed Tomography Angiography (CTA)(American College of Radiology, Radiological Society of North America)
Also available in Spanish
- Duplex Ultrasound(Society for Vascular Surgery)
- MR Angiography (MRA)(American College of Radiology, Radiological Society of North America)
Also available in Spanish
- Ultrasound - Vascular(American College of Radiology, Radiological Society of North America)
Also available in Spanish
- Treatment
- Amputation(Society for Vascular Surgery)
- Angioplasty and Stenting(Society for Vascular Surgery)
- Antiplatelet Drugs(Cleveland Clinic Foundation)
- Endarterectomy(Society for Vascular Surgery)
- Surgical Bypass(Society for Vascular Surgery)
- Thrombolytic Therapy(Society for Vascular Surgery)
- Prevention/Screening
- PAD Risk Factors and Possible Complications(American Heart Association)
- Specific Conditions
- Aortoiliac Occlusive Disease(Society for Vascular Surgery)
- Arm Artery Disease(Society for Vascular Surgery)
- Buerger's Disease(Mayo Foundation for Medical Education and Research)
- Critical Limb Ischemia: What Is It?(Vascular Disease Foundation)
- Facts about Peripheral Arterial Disease (P.A.D.) for African Americans(National Heart, Lung, and Blood Institute) - Links to PDF
- Functional Peripheral Arterial Disease(Merck & Co., Inc.)
- Gangrene(Mayo Foundation for Medical Education and Research)
- JAMA Patient Page: Renal Artery Stenosis(American Medical Association) - Links to PDF
- Occlusive Peripheral Arterial Disease(Merck & Co., Inc.)
- Peripheral Aneurysms(Society for Vascular Surgery)
- Related Issues
- About Peripheral Arterial Disease(Peripheral Arterial Disease Coalition) - Links to PDF
- Claudication(Mayo Foundation for Medical Education and Research)
- Peripheral Arterial Disease (PAD) and Limb Loss
(Amputee Coalition of America) Also available in Spanish
- Vascular Pain(Cleveland Clinic Foundation)
- Health Check Tools
- Are You at Risk for Peripheral Arterial Disease (PAD)?(Society of Interventional Radiology)
- Videos
- Cryoplasty Therapy: Innovative Technique to Remedy Blood Vessel Blockage Resulting from Peripheral Arterial Disease(OR-Live) - One hour program - 5/02/2007
- Procedures for Improving Circulation to the Legs(OR-Live) - One hour program - 5/10/2007
- Clinical Trials
- ClinicalTrials.gov: Intermittent Claudication(National Institutes of Health)
- ClinicalTrials.gov: Peripheral Vascular Diseases(National Institutes of Health)
- ClinicalTrials.gov: Intermittent Claudication
- Research
- Insulin Resistance Linked to Peripheral Artery Disease(American Heart Association)
- Secondhand Smoke Linked to Peripheral Artery Disease in Women(American Heart Association)
- Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Aspirin for the prevention of cardiovascular events in patients with...
- Article: Bosentan: new indication. Scleroderma and finger ulcers: no tangible efficacy.
- Article: Exercise, especially treadmill, eases peripheral artery trouble.
- Peripheral Arterial Disease -- see more articles
- Directories
- Find a Peripheral Vascular Disease Screening Site(Society of Interventional Radiology)
- Find a Vascular Specialist(Society for Vascular Surgery)
- Find an Accredited Echocardiography Laboratory or Vascular Laboratory(American Society of Echocardiography)
- Organizations
- American Heart Association
- National Heart, Lung, and Blood Institute
- Society of Interventional Radiology
- MedlinePlus Magazine
- It Hurts When I Walk!
- Peripheral Arterial Disease Can Be a Killer
- Prevent P.A.D.: Know Your Numbers
- Treating P.A.D.
- Your P.A.D. Checklist
- It Hurts When I Walk!
- Women
- Women and Vascular Disease(Society of Interventional Radiology)
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Related Topics
- Carotid Artery Disease
- Deep Vein Thrombosis
- Varicose Veins
- Vascular Diseases
- Blood, Heart and Circulation
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National Institutes of Health
- The primary NIH organization for research on Peripheral Arterial Disease is the National Heart, Lung, and Blood Institute
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Languages
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